Paracetamol Capsules (Spasmed)

TRAMADOL HCl — 50 mg / capsule

Opioid Analgesic / SNRI

Binds to µ-opioid receptors and inhibits serotonin & norepinephrine reuptake. Blocks pain signal transmission to the brain for broad-spectrum pain relief.

ACETAMINOPHEN (APAP) — 325 mg / capsule

Non-opioid Analgesic / Antipyretic

Inhibits prostaglandin synthesis in the CNS. Reduces pain perception and fever without affecting the GI tract — complements tramadol’s opioid action.

DICYCLOMINE HCl — 10 mg / capsule

Anticholinergic / Antispasmodic

Blocks acetylcholine at smooth muscle nerve endings. Directly relaxes GI tract muscles, relieving cramping, spasms, bloating, and discomfort.

Tramadol Hydrochloride  —  50 mg

Drug Class

Opioid Analgesic / SNRI

Primary Action

Blocks pain signals to brain; µ-opioid agonist

Acetaminophen (APAP)  —  325 mg

Drug Class

Non-opioid Analgesic / Antipyretic

Primary Action

Inhibits prostaglandin synthesis centrally

Dicyclomine Hydrochloride  —  10 mg

Drug Class

Anticholinergic / Antispasmodic

Primary Action

Relaxes smooth muscles of GI tract; stops spasms

Why a triple combination? Tramadol addresses central pain perception; Acetaminophen provides analgesic and antipyretic cover; Dicyclomine targets smooth muscle spasms — together delivering more comprehensive relief than any single agent alone.

Tramadol HCl

Onset

30 – 60 min

Duration

4 – 6 hours

Acetaminophen (APAP)

Onset

~30 min

Duration

4 – 6 hours

Dicyclomine HCl

Onset

60 – 90 min

Duration

4 hours

💡 Tips for Best Results

• Take with a light meal or glass of water to reduce stomach upset.
• You may begin to feel relief within one hour of taking a capsule.
• Avoid alcohol — intensifies drowsiness and increases liver damage risk.
• Do not take with other paracetamol/acetaminophen-containing products.

Adults (≥18 years)

Dose

1 – 2 capsules per dose

Frequency

Every 4 – 6 hours as needed

Max/Day

8 capsules — short-term use only

Elderly Patients

Dose

1 capsule — start low, monitor closely

Frequency

Every 6 hours

Renal / Hepatic Impairment

Use with caution; dose adjustment may be required. Avoid in severe liver disease.

⛔ Children under 18

Not recommended — safety and efficacy not established

Very Common

Nausea, vomiting, dry mouth, dizziness, drowsiness, blurred vision, weakness

Common

Constipation, nervousness, headache, sweating, fatigue, loss of appetite

Uncommon

Confusion, palpitations, urinary retention, skin rash, hallucinations

Rare

Seizures, severe liver reactions, anaphylaxis, drug dependence (tramadol)

⚠ Important Safety Warnings

• Habit-forming: Tramadol has potential for dependence and abuse. Use only for duration advised.
• Acetaminophen overdose: Do not take with any other product containing paracetamol or acetaminophen.
• Seizure risk: Increased in patients taking SSRIs, tricyclics, or with history of epilepsy.
• Driving: Dicyclomine and Tramadol may cause drowsiness and blurred vision. Do not drive until you know how this medicine affects you.

⛔ Known allergy to any of the three active ingredients

⛔ Severe liver disease or active liver damage

⛔ Obstruction of urinary tract or GI tract

⛔ Currently taking or within 14 days of MAO Inhibitors

⛔ Glaucoma (elevated eye pressure)

⛔ Pregnancy or breastfeeding — consult doctor first

⛔ Myasthenia gravis (muscle weakness condition)

⛔ Uncontrolled epilepsy

Temperature

Store below 25°C in a cool, dry place

Light & Moisture

Keep in original packaging. Do not store in bathrooms.

Expiry

Check date on box. Do not use after expiry date.

Children

Keep out of sight and reach of children

Disposal

Return unused capsules to pharmacy. Do not flush or dispose in household waste.

Brand Name

Spasmed

Manufacturer

M/S Admera Labs

Composition

Dicyclomine HCl 10mg + Tramadol HCl 50mg + Acetaminophen 325mg

Dosage Form

Hard Capsules

Pack Size

10 × 3 × 8 = 240 capsules per box

Batch No.

BGCL-112

Expiry Date

08-2027

Prescription Status

NRx (Non-Refillable Prescription)